IFOM is an internationally recognized non-profit cancer research institute supported by the Italian Association for Cancer Research (AIRC) based in Milan within a highly dynamic urban environment.
IFOM's continuous success is ensured by the recruitment of highly-competitive undergraduate, graduate and post-graduate researchers worldwide, with over 24 countries currently represented in IFOM.
IFOM labs are hosted within a research campus shared with the European Institute of Oncology and the Italian Institute of Technology.
IFOM is committed to creating a safe and inclusive work environment, based on mutual respect and on the enhancement of diversity, offering equal job opportunities to all qualified candidates.
We are recruiting for our Institute a
Post-doctoral Research Scientist
About the position
We are seeking a highly motivated, independent postdoctoral researcher to join our team.
The selected candidate will be responsible for:
Design and execute CRISPR-knockout (CRISPR-KO) and CRISPR-mediated base editing screens to investigate novel targets and biomarkers in cancer immunity.
Perform experimental approaches to study DNA damage response (DDR) pathways and their role in tumor-immune interactions.
Generate, analyze, and interpret data to drive discovery and publications.
Drafting scientific manuscripts and contributing to the overall preparation of research for publication.
Collaborate with other laboratories.
Attend national and international meetings to present research findings and learn the latest advances in the field.
Department overview
The position is in the Leuzzi Lab:
Our research: Cancer cells are not invisible to the immune system, but many find ways to hide.
Some exploit DNA damage response (DDR) pathways to suppress immune activation, while others accumulate mutations that reshape their interaction with immune cells.
Understanding these mechanisms is critical for developing new therapies that enhance the immune system's ability to target tumors.
The Leuzzi Lab investigates how DNA repair mechanisms and genome instability shape tumor-immune interactions, aiming to uncover novel strategies to enhance cancer immunotherapy.
Our lab employs an interdisciplinary approach, combining CRISPR-based genome engineering, high-throughput functional genomics, multi-omics analyses, and in vivo models to dissect these critical processes.
Profile Description
We are seeking a highly motivated, independent postdoctoral researcher to join our team.
The successful candidate will thrive in our collaborative, international research environment, which offers access to cutting-edge technologies and strong institutional support.
This position provides an exceptional opportunity to develop innovative projects at the intersection of cancer biology and tumor immunology, gains hands-on experience in high-throughput functional genomics, while advancing your scientific career in a highly supportive and stimulating setting.
Language skills
Proficiency in English for speaking and writing - English is the working language at the Institute.
Required skills
Extensive knowledge in DNA repair or CRISPR-based screening approaches;
Self-motivation and a curiosity-driven mindset;
Strong publication record, including at least one publication in the last year with the applicant as principal author.
Great communication skills and strong motivation to work in a collaborative and constructive lab environment.
Educational experience
PhD in Molecular biology, Cancer biology, Genetics or related area.
What we offer
International work environment; Flextime; Guest house inside the Campus
Agreements with discounts for Gym, Pharmacy, Psychology service and various shops around Ifom area; Bar and canteen inside the campus & lunch agevolazioni; Company Nursery
Continuous support to candidates and their families (including homing, schooling, registration to the national health system, work permit etc.) thanks to the activities of the Welcome office
Medical Service; Laptop; Caf service- tax declaration.
Type of Contract
Annual renewable fellowship (post-doc).
The candidate will be offered a competitive salary, commensurate with skills and working experience.
Location
Milan – Scalo di Porta Romana area
Contacts
Candidates should send:
CV;
Cover letter describing your previous research, your research interests and motivation for joining our team.
Contact details for two/three references to:
Consideration of applications will begin as they are received and will continue until the position is filled.
This job advertisement is addressed to both genders in accordance with Laws ****** and ****** and to individuals of all ages and nationalities in accordance with Legislative Decrees ****** and ******.
Disclaimer privacy
ENG - (Article 13 of the EU Regulation ********) We inform you that the archiving and processing of data referring to you are carried out by IFOM - Istituto Fondazione di Oncologia Molecolare ETS in order to perform the recruitment process.
Pursuant to Article 6(1)(b) the legal basis for the processing is the necessity to take steps at the request of the data subject prior to entering into a contract.
Your data shall be communicated to third parties that could be located in countries outside the European Union for the recruitment process.
IFOM has obtained the necessary guarantees to transfer the Data in compliance with the provisions of Chapter V of the GDPR.
The resumes received will be deleted at the end of the calendar year following the one of receipt; if you are still interested in proposing your application you will have to re-send.
According to Article 15 et seq of the EU Regulation ******** to exercise your rights you can write to the Data Controller: IFOM - Istituto