H3Postdoc position in Structural Biology for Drug Discovery /h3 ul liSalary: 2,500,000 L /li liProject: Development of novel small molecules that inhibit the growth of early-stage melanoma tumors /li liCommitment contract: Collaboration contract, 12 months - renewable /li liLocation: Genova, Italy /li /ul h3WHO WE ARE /h3 pAt IIT, we are committed to advancing human-centered Science and Technology to address the most urgent societal challenges of our era. We foster excellence in both fundamental and applied research, spanning fields such as neuroscience and cognition, humanoid technologies and robotics, artificial intelligence, nanotechnology, and material sciences, offering a truly interdisciplinary scientific experience. Our approach integrates cutting-edge tools and technology, empowering researchers to push the limits of knowledge and innovation. With us, your curiosity will know no bounds. /p pWe are dedicated to providing equal employment opportunities and fostering diversity in all its forms, creating an inclusive environment. We value the unique experiences, knowledge, backgrounds, cultures, and perspectives of our people. By embracing diversity, we believe science can achieve its fullest potential. /p h3THE ROLE /h3 pYou will work in a multicultural and multi-disciplinary group, where junior and senior scientists collaborate, each with their expertise, to carry out a shared research goal. /p pThe Molecular Modeling and Drug Discovery Research Unit is coordinated by Dr. Marco De Vivo, an expert in computational and medicinal chemistry and biochemistry for drug discovery. /p h3Responsibilities include: /h3 ul liCharacterization of the activity and mechanism of action of small molecules in vitro using enzyme-based assays /li liProtein crystallization and structure determination /li liCharacterization of the mechanism of action of small molecules in mammalian cell-based assays using human cancer cell lines /li liCharacterization of protein-protein and/or protein-ligand interactions using biophysical methods like ITC, MST, SPR, etc. /li /ul h3ESSENTIAL REQUIREMENTS /h3 ul liPhD in Biology, Biochemistry, Biophysics, Biotechnology, or related fields, with a strong research record /li liExperience in structural biology /li liHands-on knowledge of molecular biology techniques such as cloning, site-directed mutagenesis, PCR, western blotting /li liFamiliarity with imaging techniques and quantitative image analysis /li liStrong publication record relevant to experience level /li liAbility to organize and publish research data effectively /li liExperience in mentoring junior scientists /li liProficiency in spoken and written English /li /ul h3ADDITIONAL SKILLS /h3 ul liGood communication skills /li liProblem-solving attitude /li liMotivation to learn /li liCreativity and innovation /li liTime and priority management /li liAbility to work independently and in a collaborative, interdisciplinary environment /li /ul h3COMPENSATION PACKAGE /h3 ul liCompetitive salary based on experience and expertise /li liPrivate healthcare coverage /li /ul pThis position is funded by AIRC - Associazione Italiana per la ricerca sul cancro, within the project on RHOA interaction inhibitors for early-stage melanoma tumors. Reference: 30631, CUP J53C24004460007. /p h3Application deadline: February 19, 2025 /h3 h3Primary Location /h3 pGenova Erzelli /p h3Organization /h3 pMolecular Modeling and Drug Discovery /p h3Job Posting Date /h3 pFebruary 4, 2025 /p #J-18808-Ljbffr