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Research bioinformatician

Milano
Human Technopole
Pubblicato il 31 luglio
Descrizione

Human Technopole (HT) is an interdisciplinary life science research institute, created and supported by the Italian Government, with the aim of developing innovative strategies to improve human health. HT is composed of five Centers: Computational Biology, Structural Biology, Genomics, Neurogenomics and Health Data Science. The Centers work together to enable interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.

The Human Technopole Foundation is looking for a Senior Bioinformatician in the lab of Prof. Giuseppe Testa, Neurogenomics Research Centre ( Testa Group - Human Technopole ). The lab conforms its activity to the highest standards of reproducibility and transparency of the FAIR paradigm (Findable, Accessible, Interoperable and Reusable). It benefits from a state-of-the-art High-Performance Computing infrastructure, and from close interaction with an expert community of computational and experimental biologists and the transformative core facilities of HT, as well as computational support units such as the CEll REference BRain Atlas (CEREBRA) Scientific Support Units.


See previous work on the research topics of this call:
An integrated transcriptomic cell atlas of human neural organoids. Caporale N, Leonardi O, Villa CE, Vitriolo A, Boeckx C, Testa G: Tile by tile: capturing the evolutionary mosaic of human conditions. GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.Science Advances 9, eadh2726 (2023).
Science 375, eabe8244 (2022).
We are looking for a highly-motivated Senior Bioinformatician who will provide computational support for projects focused on the high definition modelling of neurodevelopmental disorders through the integration of brain organoid, technologies and a wide suite of multi-omic, imaging and functional assays.


Establishing and maintaining reproducible and well-documented bioinformatic pipelines for the standardised analysis of internal and external single cell multi-omics datasets.
Contributing to the design and development of bespoke data portals and data navigation/visualization solutions.
Maintaining and documenting software, following best practices of software engineering (e.g., MSc in a quantitative field (bioinformatics, computer science, statistics, mathematics, physics, engineering or similar);
Proficiency in at least one of the following programming languages: Python (preferable), R, java, javascript, C++, C#, MATLAB;
Proficiency with code versioning systems (e.g., experience working in a Unix/Linux environment;
Experience in bioinformatics workflow systems (i.e., Fluency in English – HT is an international research institute

A PhD degree and/or years of work experience in a data science/software engineering related role;
Previous experience in the analysis of single cell omics datasets and an interest in neurobiology (or previous experience in the field);
Expertise in the following areas: web frameworks for data visualization, dashboards, database, data management.

Organizational and social skills:
Please apply online by sending:
i) a CV in English
ii) a motivation letter in English
For any inquiry about the call, please feel free to contact Prof. Why Human Technopole
HT seeks scientific excellence, we recruit the best scientific talents through international, open calls.
Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches.
We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

Italian language training for foreigners.
Possibility of flexible working hours
Support for relocation.
Tax benefits where applicable.

Contract offered: CCNL Chimico Farmaceutico, Employee level, 3 years fixed-term.
the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and/or obstructive circumstances.

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