Posizione
The Chemical Biology Lab at the Italian Institute for Genomic Medicine (IIGM) is seeking highly motivated candidates at all levels of seniority (predoc, postdoc) to work in functional genomics and epigenetics within the context of gastrointestinal cancer research. The laboratory investigates key aspects of drug tolerance and its involvement in tumor recurrence, with a focus on a subset of cancer cells that can survive therapy by entering a reversible, slow- proliferative state that is challenging to target with standard treatments. The project aims to identify the underlying biological mechanisms and apply research findings to develop potential therapeutic strategies. The Institute provides state-of-the-art Genomics and single-cell Genomics Sequencing platforms.
The successful candidate will take on the following responsibilities:
• conduct CRISPR-based functional screening using patient-derived cancer tumoroids;
• optimize protocols and strategies for FACS-based functional genomics screening;
• contribute to ongoing research group activities and collaborative projects
Interested candidates should include:
• curriculum vitae (in PDF format in Italian or English)
• cover letter
• research proposal (for postdoc applicants only)
• certificates, transcripts including all grades of your previous qualifications, and a list of publications
Competitive remuneration based on the candidate’s personal qualifications.
Caratteristiche del candidato
Lingue straniereE' richiesta la conoscenza delle seguenti lingue
1. Inglese: ottimo (C2)
Esperienze lavorative precedentiBachelor’s degree in biotechnology, biology, medicine, chemical biology, pharmacy or a related field; 1 year experience in at least one of the following subjects:
(i) molecular cloning
(ii) pooled genetic screening
(iii) flow cytometry
(iv) mammalian tissue culture (cells and/or organoids)
Soft skills:
• curiosity and active learning
• critical thinking and problem-solving time management
• adaptability and flexibility
• effective communication in cross-cultural environmentsTitoli preferenzialiknowledge of Italian is an advantage, but not strictly necessaryTitolo di studioLaurea (primo livello)Area disciplinarescientifico,chimico-farmaceutico,geo-biologico,medicoClasse di laureaBiotecnologie (L-2, 1)
Scienze biologiche (L-13, 12)
Scienze e tecnologie chimiche (L-27, 21)
Scienze e tecnologie farmaceutiche (L-29, 24)Tipo candidatoLaureato con esperienza