Orano Med is a biotechnology company owned by Orano. Our ambition is to develop a new generation of targeted cancer therapies using the unique properties of lead-212, a rare alpha-emitting radioisotope with highly promising medical properties. Responsabilities In collaboration with the Discovery team, build and apply cheminformatics and computational chemistry capabilities to support the Design-Make-Test-Analyze (DMTA) discovery cycle in radiotheranostics. Contribute to the advancement of the radiotheranostic pipeline by applying computational approaches such as molecular docking, ligand-based design, diversity and conformational analyses, together with machine learning and AI methods, to support multiparameter optimization of radioligand candidates. Develop, optimize, and implement computational tools, workflows, and methods (e.g., docking, molecular dynamics, free-energy calculations, ML/AI-assisted design) to strengthen internal discovery capabilities and accelerate project progression. Provide computational support and scientific input across key discovery stages, including target assessment, hit identification, and lead optimization, working closely with medicinal chemistry and biology teams. Collaborate with the IT and data science teams to help integrate AI-enabled tools into day-to-day drug design workflows. Clearly communicate computational results, design hypotheses, and data-driven recommendations to multidisciplinary project teams. For the time being, the position will be based in Chatillon, but in March the site is scheduled to move to Villejuif.,
Opérateur international reconnu dans le domaine des matières nucléaires, Orano apporte des solutions aux défis actuels et futurs, dans l'énergie et la santé.
Son expertise ainsi que sa maîtrise des technologies de pointe permettent à Orano de proposer à ses clients des produits et services à forte valeur ajoutée sur l'ensemble du cycle du combustible.
Grâce à leurs compétences, leur exigence en matière de sûreté et de sécurité et leur recherche constante d'innovation, l'ensemble des collaborateurs du groupe s'engage pour développer des savoir-faire de transformation et de maîtrise des matières nucléaires, pour le climat, pour la santé et pour un monde économe en ressources, aujourd'hui et demain.
Orano, donnons toute sa valeur au nucléaire.
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